The inner membrane of mitochondria exhibits a unique three dimensional structure. It is also exceptionally rich in proteins, most of which facilitate transport and catalytic processes. Currently, it is assumed that the structure of the inner membrane enables dedicated protein and lipid environments resulting in the spatial organization of protein functions. Accordingly, protein function and membrane topology appear to be tightly intertwined with each other in mitochondria.
Considering this, it is surprising that we still lack detailed insight into how the inner membrane is shaped. Moreover, information on the actual distribution of protein functions in the inner membrane is very scarce at the best. To this end, experimental approaches that provide temporal and spatial information of inner membrane shape and protein localisations are essential to assess and eventually understand how membrane shape and functional organization are brought about. The combination of functional analyses with state-of-the-art microscopy allows to obtain a detailed view on the organization of the inner membrane, to address the question on how proteins support the shaping of the inner membrane, and to define how these processes are interconnected and regulated in the cellular context.
This conference brings together experts with unique expertise in mitochondrial imaging technologies with scientists addressing central biological questions on mitochondrial functions.
University of Padua, Padua, IT
IMOL Institute, Warschau, PL
Max-Planck-Institut für Biophysik, Frankfurt/Main, GER
Heinrich Heine University, Düsseldorf, GER
Universität Kaiserslautern, Kaiserslautern, GER
, Forschungszentrum Jülich GmbH, Jülich, GER
Opening
09:00 - 09:10
"Proteolytic rewiring of mitochondria in hypoxia"
09:10 - 09:35
"A selectivity filter in Tim17 mediates intramitochondrial protein sorting"
09:35 - 10:10
"Mitochondrial machineries linking membrane compartmentalization, protein biogenesis
and metabolism"
10:10 - 10:35
10:35- 11:05
"Assembly mechanism and compositional diversity of mammalian supercomplexes"
11:05 - 11:40
tba
10:40 - 12:05
"Driving protein import into mitochondria"
12:05 - 12:30
12:30- 13:30
"Visualising dynamic processes at mitochondria"
13:30 - 14:05
tba
14:05 - 14:30
"How mitochondria stay in shape"
14:30 - 14:55
"Mitochondrial Signaling Platforms Regulated by Ubiquitin"
14:55 - 15:20
15:20 - 17:00
"Keeping Mitochondria in Shape: A Matter of Life and Death"
17:00 - 18:00
18:30 at "Alte Mensa"
"Checkpoints in protein import into mitochondria"
09:00 - 09:35
"Live-Cell STED Microscopy of Mitochondria: How New Labeling Strategies Enable Visualization
of Mitochondrial Ultrastructure"
09:35 - 09:50
"A multiplexed approach for genetic screening of human cells by electron microscopy
uncovers a critical effector of mitochondrial cristae shape"
09:50 - 10:05
"The role of Gasdermins in mitochondrial apoptosis"
10:05 - 10:20
"Coupling translation to membrane insertion of mitochondrial-encoded proteins"
10:20 - 10:35
10:35 - 11:00
"Metabolic Parameters driving cristae membrane dynamics"
11:00 - 11:35
"Context-dependent heterogeneity of neuronal mitochondria in a leukodystrophy
mouse model"
11:35 - 12:00
tba
12:00 - 12:25
"Charting the inner mitochondrial membrane through in situ structural biology"
12:25 - 12:50
Closing remarks
12:50 - 13:00
The registration fee is 75€ for PhDs and 99€ for postdocs and senior researchers. Symposium attendance as well as meals and drinks are included in the fee.
All necessary information and application for a presentation is provided there. Based on these submissions, the selected candidates will be asked to present their poster in a talk.
After submission, confirmation of registration and payment instructions will be provided by email.
Please be informed that payment is by bank transfer ONLY. Unfortunately, payments with credit cards or PayPal will not be accepted.
Do not hesitate to contact us if you have any other inquiries. Registration is closed.
Göttingen – This lively university town with a historical charm is very popular with travelers and tourists, so be sure to book your accommodation well in advance.
A certain number of rooms have been reserved at the Four Points by Sheraton Göttingen (Bahnhofsallee 1a, 37081 Göttingen, Germany). Make your reservation by 26 January 2026 via this link (reservations are made on a first-come, first-served basis).
Please note that we do not specifically recommend any hotels. Other hotels within a reasonable distance to the venue “Alte Mensa” include the following:
The following web pages provide some additional information about Göttingen, accommodation and also about public transport in Göttingen:
Tagungs- und Veranstaltungshaus "Alte Mensa"
Hannah-Vogt-Saal und Emmy-Noether-Saal
Wilhelmsplatz 3
37073 Göttingen
Germany
The Alte Mensa is located in the heart of Göttingen city centre, just a 15-minute walk from the railway station. The bus lines 41, 42, 50 and 72 also run regularly from the station to the nearest bus stop "Jüdenstraße".
To reach the Alte Mensa from the Four Points by Sheraton hotel, you can either take buses 31 or 32, which run regularly between the “Otto-Frey-Brücke” and “Jüdenstraße” bus stops, or walk for 20 minutes.
If you need further information about the conference, the payment, the registration or if you have any other question, do not hesitate to contact us!
University Medical Faculty / MPI for Biophysical Chemistry, Göttingen, GER
Administrative Coordinator, MPI for Multidisciplinary Sciences, Göttingen, GER
Scientific Coordinator, University Medical Faculty / Fraunhofer ITMP TNM, Göttingen, GER
